BDBM151186 US8987313, 8

SMILES CC(C)c1nc(CN(C)C(=O)N2C[C@@H](O)C[C@H]2C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1

InChI Key InChIKey=WAWNWRVGWKZVLT-CFTUFJLTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151186   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM151186(US8987313, 8)
Affinity DataIC50:  240nMT: 2°CAssay Description:The potencies of the compounds as inhibitors of human hepatic cytochromes P450 of the CYP3A subfamily (particularly CYP3A4) were assessed using well-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM151186(US8987313, 8)
Affinity DataIC50:  170nMT: 2°CAssay Description:The potencies of the compounds as inhibitors of human hepatic cytochromes P450 of the CYP3A subfamily (particularly CYP3A4) were assessed using well-...More data for this Ligand-Target Pair
In DepthDetails US Patent